Latest Issue
      2023 Year 04 Issue

        Full Length Article

      • Zhao Geng, Ling Gao, Chongyi Li, He Xiao, Liqi Fan, Pei Liu, Juan Yu, Rongdi Yuan, Jian Ye
        2023, 3(04): 153-158. DOI: 10.1016/j.aopr.2023.07.002
        Abstract：PurposeTo explore the effect of the variation of pupil diameter (PD) and intraocular pressure (IOP) induced by femtosecond laser treatment on the subsequent phacoemulsfication and intraocular lens implantation. And whether the application of 0.1% pranoprofen could significantly reduce the miosis and increased IOP caused by femtosecond laser treatment in femtosecond laser-assisted cataract surgery (FLACS).  
        Keywords：Pupil diameter; Intraocular pressure; Femtosecond; Cataract   
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        Published：2023-08-30
      • Hao Wang, Qiang Ye, Weihe Xu, Jing Wang, Jianhan Liu, Xintong Xu, Wenfang Zhang
        2023, 3(04): 159-170. DOI: 10.1016/j.aopr.2023.07.003
        Abstract：BackgroundRandomized controlled trials (RCTs) are often considered the gold standard and the cornerstone for clinical practice. However, bibliometric studies on worldwide RCTs of ophthalmology published in the 21st century have not been reported in detail yet. This study aims to perform a bibliometric study and visualization analysis of worldwide ophthalmologic RCTs in the 21st century.  
        Keywords：Ophthalmology; Randomized controlled trials (RCTs); The 21st century; Worldwide; Bibliometric; Research trends   
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        Published：2023-08-30

        Review

      • Qiyu Qin, Chengshou Zhang, Naiji Yu, Fan Jia, Xin Liu, Qi Zhang, Min Chen, Kaijun Wang
        2023, 3(04): 171-179. DOI: 10.1016/j.aopr.2023.09.001
        Abstract：BackgroundGlaucoma is the leading cause of irreversible blindness worldwide. The reduction of intraocular pressure has proved to be the only factor which can be modified in the treatment, and surgical management is one of the important methods for the treatment of glaucoma patients.  
        Keywords：Glaucoma drainage devices; Minimally invasive glaucoma surgery; Material characteristics   
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        Published：2023-10-21
      • Zaoxia Guo, Xiaopan Ma, Rui Xue Zhang, Hong Yan
        2023, 3(04): 180-186. DOI: 10.1016/j.aopr.2023.10.001
        Abstract：BackgroundCataract is a blinding disease worldwide. It is an age-related disease that mainly occurs in people over 65 years old. Cataract is also prevalent in patients with diabetes mellites (DM). The pathological mechanisms underlying diabetic cataract (DC) are more complex than that of age-related cataract. Studies have identified that polyol pathway, advanced glycation end products (AGEs) and oxidative stress are the primary pathogenesis of DC. In recent years, molecular-level regulations and pathological processes of lens epithelial cells (LECs) have been confirmed to play roles in the initiation and progression of DC. A comprehensive understanding and elucidation of how chronic hyperglycemia drives molecular-level regulations and cytopathological processes in the lens will shed lights on the prevention, delay and treatment of DC.  
        Keywords：Oxidative stress; Epigenetic regulation; Autophagy; Fibrosis; Apoptosis; Diabetic cataract   
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        Published：2023-10-21
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