Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women

Hanfei Wu; Haishuang Lin; Mengting Ruan; Huanjie Fang; Nannan Dong; Tiewei Wang; Feifei Yu; Jiawei Zhao

doi:10.1016/j.aopr.2023.12.001

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Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women

Full Length Article | 更新时间：2024-05-29

- Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women
- AOPR Vol. 4, Issue 1, Pages: 8-13(2024)
- 作者机构：
  
  1. Department of Opthalmology, The People's Hospital of Zhuji,Zhejiang,Shaoxing,China
  2. Department of Opthalmology, The Second Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,China
  3. Department of Obstetrics, The People's Hospital of Zhuji,Zhejiang,China
- 作者简介：
- 基金信息：
- DOI：10.1016/j.aopr.2023.12.001
  CLC：
- Published：2024，
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Hanfei Wu, Haishuang Lin, Mengting Ruan, et al. Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women. [J]. AOPR 4(1):8-13(2024)
DOI：

Hanfei Wu, Haishuang Lin, Mengting Ruan, et al. Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women. [J]. AOPR 4(1):8-13(2024) DOI： 10.1016/j.aopr.2023.12.001.

摘要

Abstract

PurposeTo evaluate choroidal thickness and retinal nerve fiber layer (RNFL) thickness in different trimesters using enhanced depth imaging optical coherence tomography (EDI-OCT).MethodsA prospective comparative study included 45 healthy pregnant women in the first trimester

45 women in the second

45 women in the third and 45 healthy non-pregnant women as the control group. Macular choroidal thickness was measured at three locations: The subfoveal

1 mm temporal

and 1 mm nasal from the fovea with EDI-OCT. Peripapillary choroidal thickness (PPCT) and RNFL thickness parameters were automatically calculated by the Spectralis OCT.ResultsThe subfoveal

temporal and nasal macular choroidal thickness were all significantly thicker in the second trimester

compared with those parameters in the first

the third trimesters and the control group (all

0.05). The PPCT was significantly increased in the second trimeter compared with the control group at global

temporal

temporal inferior

nasal and nasal inferior positions (all

0.05). The RNFL thickness was also significantly increased in

pregnant women at nasal superior and nasal inferior quadrants (all

0.05).ConclusionsThe choroidal thickness in pregnant women was found to be thicker than the control group

regardless of macular or optic disc location. Findings of RNFL thickening might indicate subclinical involvement of the central nervous system.

关键词

Keywords

ChoroidRetinal nerve fiber layerOptical coherence tomographyPregnancy

references

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